A Pilot Study of the Flaxseed Effects on Hormones and Lignans: Role of Race, Genes, and Gut Microbiome

Susan McCann, PhD, Roswell Park Cancer Institute, in collaboration with Johanna Lampe, PhD, Fred Hutchinson Cancer Research Center
Study review

The purpose of this study was to determine whether adding flaxseed (a food high in compounds that can change hormones) to a regular diet changes hormones that are related to breast cancer risk and if the effect of flaxseed differs between African- American and Caucasian women. The researchers turned to the Army of Women (AOW) to enroll up to 200 volunteers from the Buffalo, New York area. The Call to Action for this study was sent to AOW members on July 24, 2013. The researchers closed enrollment on February 3, 2017, after the AOW provided them with 35 women who were interested in enrolling in the study.