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Daughters, dUdes, mothErs, and others fighting cancer Together (DUET)

Researcher
Wendy Demark-Wahnefried, PhD, RD; Dorothy Pekmezi, PhD; Robert Oster, PhD; Teri Hoenemeyer, PhD; Laura Rogers, MD; University of Alabama at Birmingham
Summary

Studies have found that cancer survivors who are overweight have a higher risk of having their cancer come back.  This study is enrolling overweight or obese (BMI>25) survivors of colorectal, kidney, prostate, ovarian, uterine, multiple myeloma, or female breast cancer along with a friend or relative (buddy) who is overweight or obese who live in Alabama, Mississippi, North Carolina, or Tennessee. The researchers want to learn how a weight loss and exercise program affects the health behaviors of cancer survivors and the people around them, as well their overall health and quality of life.

What does participation involve?

This is a 6-month study that can be completed entirely from your own home (no need to travel). If you and your buddy think you are eligible and agree to participate in this study, you will be contacted by a member of the research team to discuss the study and answer a series of questions to ensure your eligibility. You and your partner will be randomly assigned (like the flip of a coin) to one of two groups, the exercise and weight loss program or a waitlisted group.

If you and your partner are assigned to the exercise and weight loss group, you will start a program that will be delivered online and via text messages. You will also receive diet and exercise supplies from the research team. Before you start the program, after 3 months, and at 6 months, when the program ends, you will complete a two-part internet-based survey. Each part will take about 30 to 45 minutes to complete. In addition, at the start of the program and at the end of the program, the research team will ask you and your buddy to attend either two community health center visits or two health assessments done in your home. Each visit will last about 1 hour. Prior to these visits, you will wear an activity monitor (provided by the research team) for a week. During these visits, a member of the research team will take your blood pressure, weight, height, and waist size. They will also ask you to complete a few physical function tests and will draw 2 tablespoons of your blood.

If you are assigned to the waitlisted group, you and your partner will receive monthly newsletters, and after 6 months, you both will receive supplies and access to the online program.

Where?
Alabama, Mississippi, North Carolina, and Tennessee
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